The cost of treatment depends on the type of program, length of stay, and location. A single ketamine infusion session in the U.S. typically ranges from $300 to $800, while a series of treatments may cost between $3,000 and $6,000. Residential programs for substances like psilocybin or ayahuasca may range from $5,000 to $15,000, depending on the center and duration of treatment. Many centers offer financing options, but most insurance plans currently do not cover psychedelic therapy.